Nick Kroll
Nick Birch / Maury the Hormone Monster / Coach Steve / Lola Skumpy / Rick the Hormone Monster (voice)
John Mulaney
Andrew Glouberman (voice)
Jessi Klein
Jessi Glaser (voice)
Jason Mantzoukas
Jay Bilzerian (voice)
Maya Rudolph
Diane Birch / Connie the Hormone Monstress (voice)
Fred Armisen
Elliot Birch (voice)
Jordan Peele
Ghost of Duke Ellington (voice)
Andrew Rannells
Matthew (voice)
Nick Kroll
Nick Birch / Maury the Hormone Monster / Coach Steve / Lola Skumpy / Rick the Hormone Monster (voice)
John Mulaney
Andrew Glouberman (voice)
Jessi Klein
Jessi Glaser (voice)
Jason Mantzoukas
Jay Bilzerian (voice)
Maya Rudolph
Diane Birch / Connie the Hormone Monstress (voice)
Fred Armisen
Elliot Birch (voice)
Jordan Peele
Ghost of Duke Ellington (voice)
Andrew Rannells
Matthew (voice)
Nick Kroll
Nick Birch / Maury the Hormone Monster / Coach Steve / Lola Skumpy / Rick the Hormone Monster (voice)
John Mulaney
Andrew Glouberman (voice)
Jessi Klein
Jessi Glaser (voice)
Jason Mantzoukas
Jay Bilzerian (voice)
Maya Rudolph
Diane Birch / Connie the Hormone Monstress (voice)
Fred Armisen
Elliot Birch (voice)
Jordan Peele
Ghost of Duke Ellington (voice)
Andrew Rannells
Matthew (voice)
