Director: Peter Farrelly
20 years since their first adventure, Lloyd and Harry go on a road trip to find Harry's newly discovered daughter, who was given up for adoption.
Jim Carrey
Lloyd Christmas
Jeff Daniels
Harry Dunne
Laurie Holden
Adele
Rachel Melvin
Penny
Kathleen Turner
Fraida
Rob Riggle
Travis / Captain Lippincott
Tembi Locke
Dr. Walcott
Paul Blackthorne
Emergency Room Doctor
Brady Bluhm
Billy
Patricia French
Ms. Sourpuss
Steve Tom
Dr. Pinchelow
Don Lake
Dr. Meldman
Eddie Shin
Gordy
Atkins Estimond
Gus
Tommy Snider
Tom
Lindsay Ayliffe
Professor Garabedian
Matty Cardarople
Inventor No. 1
Bill Murray
Ice Pick
Grant James
Mr. Stainer
Taylor St. Clair
Mrs. Steiner
